Mutation due to Changes in Structure of Chromosome: What is Mutation? It is an abrupt and discontinuous process where a gene or chromosome undergoes a heritable change in its structure or its number. Mutations were called sports by Darwin and discontinuous variations by Bateson. The term mutation was coined by Hugo de Vries (1901). De Vries observed a number of mutations in his experimental plant Evening Primrose (Oenothera Lamarckiana). Mutation due to Changes in Structure of Chromosome (Chromosome Mutation or Chromosomal Aberration): They are changes in the morphology of chromosomes that bring about change in the number and sequence of … Continue reading Mutation due to Changes in Structure of Chromosome